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A study to compare spinal anesthesia in caesarean section when drug is given according to height and weight versus a fixed dose.

Comparison of spinal block characteristics between height and weight based dosage versus fixed dosage of intrathecal bupivacaine for elective caesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042328
Enrollment
100
Registered
2022-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Height and weight based dosage of bupivacaine: Single shot Subarachnoid block with 0.5 % hyperbaric bupivacaine based on height and weight (using Hartens chart) + 10 microgram fentanyl

Sponsors

Saveetha medical college hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient undergoing elective LSCS 2) Age 18-40 yrs 3) ASA II patients 4) Weight 50-90 kg 5) Height 140cm-180cm 6) Singleton pregnancy

Exclusion criteria

Exclusion criteria: 1) Emergency caesarean section 2) Patients refusing spinal anesthesia 3) Infection at the site of regional blockade 4) Bleeding diathesis 5) Hypersensitivity to the study drug 6) Allergy to local anaesthetics 7) Neurological diseases 8) Spinal deformities

Design outcomes

Primary

MeasureTime frame
comparison of heart rate and blood pressure between the fixed dose of bupivacaine and bupivacaine based on Hartens chartTimepoint: Baseline, pre-spinal, post-spinal, 5mins, 15mins, 30mins, 60 mins, 120 mins, post anesthesia care unit

Secondary

MeasureTime frame
APGAR score of babyTimepoint: after baby delivery and at 5 minutes after delivery;comparison of motor regression timeTimepoint: every 15 minutes;Comparison of onset of sensory blockade in both the groups Timepoint: every 30 seconds upto 10 minutes;comparison of sensory regressionTimepoint: every 15 minutes;complicationsTimepoint: every 10 minutes;quality of block assessed by surgeonTimepoint: after surgery;quality of Intraoperative analgesia assessed by patientTimepoint: once after surgery

Countries

India

Contacts

Public ContactRohit Kamal

Saveetha Medical College and Hospital

guna.kali@yahoo.com9566137571

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026