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An experimental study to validate the mathematical model developed to predict the transport of drug-like molecules across biological membranes

In silico modelling for prediction of small molecule permeability across biological membranes - an experimental validation study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/042326
Enrollment
15
Registered
2022-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M968- Other intraoperative and postprocedural complications and disorders of musculoskeletal system, not elsewhere classified

Interventions

Intervention1: Nil: Not Applicble Control Intervention1: Nil: Not Applicable

Sponsors

Apollo Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All consenting adults of any gender, age 18 years and above 2. Scheduled to undergo an orthopedic surgical procedure involving a skin incision who are likely to have excess skin during wound closure (as assessed pre-operatively by the surgeon) that would otherwise be discarded as hospital medical waste

Exclusion criteria

Exclusion criteria: 1. Those conditions where the integrity of the skin is damaged i.e trauma, crush injury etc 2. Those who are critically ill and are unable to provide consent due to any reason 3. Any other condition in the opinion of the investigator will affect the results of the experiment.

Design outcomes

Primary

MeasureTime frame
Mathematical model validationTimepoint: Baseline—

Secondary

MeasureTime frame
NoneTimepoint: Not applicable—

Countries

India

Contacts

Public ContactDr Jeffrey Pradeep Raj

Seth GS Medical College & KEM Hospital

jpraj.m07@gmail.com8095464464

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026