Health Condition 1: K088- Other specified disorders of teethand supporting structures
Conditions
Interventions
Intervention1: Nickel titanium archwire and stainless steel brackets: Nickel titanium archwires will be ligated to stainless steel brackets. Fluoridated mouthwash and toothpaste will be prescribed. Su
Sponsors
Mayur Bhola
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy subjects with minimum crowding or spacing in maxillary and mandibular arches. 2. Presence of full complement of teeth except for 3rd molars. 3. Good oral hygiene (Oral Hygiene Index-Simplified Score < 1.2).
Exclusion criteria
Exclusion criteria: 1. History of orthodontic treatment. 2. Subject who fails to maintain good oral hygiene during study period. 3. Subjects with pregnancy. 4. Subjects having any known syndrome or metabolic disorder affecting salivary glands. 5. Subjects with any oral premalignant disorders. 6. Subjects with metallic restoration or prosthesis. 7. Subjects with occupational exposure to metals. 8. Subjects on long-term medications like NSAIDs or steroids. 9. Subjects with known allergy to nickel. 10. Lack of manual dexterity. 11. Any medications for a systemic illness. 12. History of recent bacterial or viral infection. 13. Subjects who smoke or consume alcohol. 14. Subjects not willing to participate in the study.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Cell micronucleus scoring of buccal mucosa cellsTimepoint: Cell micronucleus scoring at 0 and 3 months. | — |
Primary
| Measure | Time frame |
|---|---|
| Cell viability percentageTimepoint: Cell viability percentage measured at 0 and 3 months. | — |
Countries
India
Contacts
Public ContactMayur Bhola
AIIMS, Bhubaneswar
Outcome results
None listed