Skip to content

Comparing noradrenaline and phenylephrine boluses for managing hypotension following spinal anaesthesia lower segment caeserian section

Comparison of norepinephrine and phenylephrine intravenous boluses for the treatment of hypotension following spinal anaesthesia in elective lower segment caeserian section: a randomised controlled double blind study - NO

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042301
Enrollment
60
Registered
2022-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics Health Condition 2: 1- Obstetrics Health Condition 3: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: INTRAVENOUS BOLUS DOSE OF NOREPINEPHRINE: 8 microgram of norepinephrine will be given as bolus if there is hypotension during surgery following spinal anasthesia and the duration of th

Sponsors

JLN Medical College and Hospital Ajmer
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American Society of Anaesthesiologists class â?  and class â?¡ 2. Informed consent for participation in study 3. Singleton pregnancy 4. Parturients posted for elective caesarean section

Exclusion criteria

Exclusion criteria: 1. Those unwilling to participate in study 2. Allergy or hypersensitivity to phenylephrine or norepinephrine or any study drug. 3. Height 180 cm 4. Any hypertensive disorder of pregnancy 5. Pre-existing cardiovascular or cerebrovascular disease 6. Known fetal abnormalities 7. Contraindications to spinal anaesthesia: a. Local infection at site of injection b. Any bleeding disorder c. Severe hypovolaemia d. Space occupying lesions of the brain e. Anatomical disorder of the spine f. Pre-existing liver diseases

Design outcomes

Primary

MeasureTime frame
To compare the total number of intravenous bolus doses of norepinephrine or phenylephrine required to treat spinal hypotension in parturients posted for caesarean section under spinal anasthesia and the total dose given.Timepoint: during the entire duration of surgery, and at the end of surgery

Secondary

MeasureTime frame
1.To compare the incidence of maternal bradycardia, maternal tachycardia, hypertension, nausea, vomiting, dizziness and shivering in mother. 2.To compare the fetal outcome as determined by APGAR score at 1 minute and 5 minutes. 3.Any adverse outcome or side effects. Timepoint: during the entire duration of surgery , during delivery and 5 mins afer delivery and at the end of surgery

Countries

India

Contacts

Public ContactDr Neena jain

J.L.N Medical College Ajmer

drneenaj@gmail.com9414008666

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026