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The comparison of salivary levels of specialised pro-resolving mediators,resolvins and lipoxin among smokers and non-smokers before and after non-surgical periodontal therapy

EFFECT OF PERIODONTAL THERAPY ON THE SALIVARY LEVELS OF RESOLVINS(RvE1) AND LIPOXINS(LXA4) IN PERIODONTITIS PATIENTS

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/042292
Enrollment
40
Registered
2022-04-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Non Surgical Periodontal Therapy: To compare the salivary levels of Resolvins and Lipoxins at baseline and six weeks after non surgical periodontal therapy among smokers and non-smokers

Sponsors

ARTHI I
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients with more than 20 teeth 2.Current cigarette smokers = 10 cigarettes per day 3.Periodontitis patients with probing pocket depth(PPD) = 5mm and interdental clinical attachment level(CAL) =4mm 4.Patients who are complying with oral hygiene instructions and periodontal recall 5.Patients who are willing to participate in the study

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women 2.Patients using medication affecting the periodontal status. 3.Patients with history of periodontal therapy for the past six months 4.Patients with inflammatory disorders such as rheumatoid arthritis, diabetes mellitus, COPD, inflammatory bowel disease etc.

Design outcomes

Primary

MeasureTime frame
SALIVARY LEVELS OF RESOLVIN AND LIPOXIN BEFORE AND AFTER NON-SURGICAL PERIODONTAL THERAPYTimepoint: AT BASELINE AND 4 WEEKS AFTER NON SURGICAL PERIODONTAL THERAPY—

Secondary

MeasureTime frame
To compare the salivary levels of resolvins and lipoxins before and after non-surgical periodontal therapy between smokers and non-smokers and to correlate it with clinical parameters. Timepoint: AT BASELINE AND 4 WEEKS AFTER NON SURGICAL PERIODONTAL THERAPY—

Countries

India

Contacts

Public ContactArthi I

SRM Dental College And Hospital

sangeetha_doc@yahoo.com9884563217

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026