Health Condition 1: I977- Intraoperative cardiac functionaldisturbances
Conditions
Interventions
Intervention1: 1. Inj Lignocaine hydrochloride 2% 1mg/kg
2. Inj Lignocaine hydrochloride 2% 1.5mg/kg: 1. Inj Lignocaine hydrochloride 2% 1mg/kg given intravenous stat 1 min prior to intubation.
2. I
Sponsors
Army Hospital Research And Referral
Eligibility
Inclusion criteria
Inclusion criteria: All adult patients more than 18 yrs giving valid informed consent and scheduled for elective cardiac surgery
Exclusion criteria
Exclusion criteria: a) Patient with any history of pre-existing abnormal rhythm on ECG. b) Age c) Patients with permanent pacemakers d) Patient Refusal. e) Patients undergoing emergency cardiac surgery. f) Patients undergoing complex or combined cardiac surgery. e.g. aortic surgeries, combined valvular and CABG procedures, etc. g) Patients with LVEF g) Patients with preexisting renal disease (preoperative raised Serum Creatinine more than 1.2 mg/dl). h) Anticipated Difficult Airway on preoperative assessment. (Restricted mouth opening less than 3 cm, Mallampatti Grade 3 or more, facial deformities, etc)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare different doses of intravenous lignocaine and magnesium sulphate during induction of anaesthesia to attenuate hemodynamic responses to endotracheal intubation in patients undergoing cardiac surgeryTimepoint: 1. Baseline vitals. 2. Vitals just after intubation. 3. Vitals 1min after intubation. 4. Vitals 3min Just after intubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To find optimum doses suitable and safe to attenuate hemodynamic responses to endotracheal intubation in patients undergoing cardiac surgery for better outcome of patient.Timepoint: 1. Baseline vitals. 2. Vitals just after intubation. 3. Vitals 1min after intubation. 4. Vitals 3min Just after intubation. | — |
Countries
India
Contacts
Public ContactSimrandeep Singh
Army Hospital Research And Referral, Delhi Cantt
Outcome results
None listed