Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intravenous dexmedetomidine: Intravenous dexmedetomidine (0.50mcg/kg) through an infusion pump over 40 min before induction
Control Intervention1: Intranasal dexmedetomidine: Intranasal
Sponsors
Department of Anaesthesiology SMS Medical college and attached hospitalsJaipur
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patient of ASA grade I and II. 2. Patient undergoing elective surgery (Duration 60-70 minutes)
Exclusion criteria
Exclusion criteria: 1.History of allergy to dexmedetomidine 2.History of hypertension ,CAD,renal and hepatic dysfunctional 3. Patient with intranasal pathology like nasal polyp,ulcers and deviated septum. 4.Patient not willing to participate in the study. 5.Patient with cardiac and respiratory illness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart RateTimepoint: Baseline,after loading dose then every 10min interval till 40 min,at the time of induction ,every 1min till 5 minutes after induction ,7 min after intubation,every 10 min after intubation thereafter upto 60 minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation ScoreTimepoint: Baseline,after loading dose then every 10min interval till 40 min thereafter post operatively every 1 hour upto 4 hrs;Spo2Timepoint: Baseline,after loading dose then every 10min interval till 40 min,at the time of induction ,every 1min till 5 minutes after induction ,7 min after intubation,every 10 min after intubation thereafter upto 60 minutes;Systolic BP,Diastolic BP and Mean Arterial PressureTimepoint: Baseline,after loading dose then every 10min interval till 40 min,at the time of induction ,every 1min till 5 minutes after induction ,7 min after intubation,every 10 min after intubation thereafter upto 60 minutes | — |
Countries
India
Contacts
Public ContactDr Sumaila Naaz
SMS Medical College and attached hospital,Jaipur
Outcome results
None listed