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Comparison of the relationship between cerebral oxygen saturation and mild hypercapnia in patients undergoing off- pump Coronary Artery Bypass Grafting

Prospective randomized control trial to compare the relationship between cerebral oxygen saturation and mild hypercapnia in patients undergoing off- pump Coronary Artery Bypass Grafting

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042240
Enrollment
100
Registered
2022-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I708- Atherosclerosis of other arteries Health Condition 2: I52- Other heart disorders in diseasesclassified elsewhere

Interventions

Intervention1: Prospective randomized control trial to compare the relationship between cerebral oxygen saturation and mild hypercapnia in patients undergoing off- pump Coronary Artery Bypass Grafting

Sponsors

UNMICRC
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: OPCABG, EF >40%

Exclusion criteria

Exclusion criteria: PATIENTS ON ECMO OR IABP, REDO CABG SURGERY

Design outcomes

Primary

MeasureTime frame
To investigate the relationship between mild hypercapnia and regional cerebral oxygen saturation (rSo2) during off -pump CABG.Timepoint: baseline i.e before induction, after LIMA harvesting, at each grafting proximal and distal, after protamine, after shifting in ICU?—

Secondary

MeasureTime frame
To observe intraoperative pH, bicarbonate concentration, serum potassium concentration and incidence of postoperative cognitive dysfunction.Timepoint: baseline i.e before induction, after LIMA harvesting, at each grafting proximal and distal, after protamine, after shifting in ICU, 4 hrs, 12 hrs and 24 hrs—

Countries

India

Contacts

Public ContactChanchal Bhandari

U.N.Mehta Institute of Cardiology and Research Center

chanchal.bhandari31@gmail.com9404552355

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026