Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: A dose of 50mcg dexmedetomidine diluted in 4ml normal saline will be used.
: Nebulisation will be done for a duration of 15 minutes by an ultrasonic
nebuliser with the
the help of wall
Sponsors
AIIMS Bhopal
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients (age18-65 yrs)of either gender giving consent for the study. 2.Patients of ASA grading I &II.
Exclusion criteria
Exclusion criteria: 1.Non consenting patients. 2.Allergic to dexmedetomidine or clonidine. 3.Current upper respiratory tract infections, per existing sore throat and/or hoarseness. 4.Patients using steroids or NSAIDS. 5.Patients with COPD, asthma. 6.Pregnant patients. 7.Any history of difficult intubation, loose teeth. 8.Difficult intubation requiring more than one attempt. 9.Already intubated patients. 10. Patients not extubated at the end of surgery. 11.Patients with sinus bradycardia, atrioventricular block, cardiac disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of this study will be to compare the analgesic efficacy of nebulised dexmedetomidine and clonidine in relieving post -operative sore throat.Timepoint: During the post -operative period, sore throat will be evaluated 10 minutes,1,6,12, and 24hour after extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome of this study will be to compare the effect of nebulised dexmedetomidine and clonidine on the hemodynamic parameters at the defined time point.Timepoint: Blood pressure (SBP, DBP, MAP), heart rate, spo2 will be recorded at induction, at laryngoscopy, at intubation, 1minute ,5 minute after intubation and after creation of pneumoperitoneum. Blood pressure (SBP, DBP, MAP), heart rate, spo2will also be recorded just after extubation and 1,6,12,24 hours after extubation | — |
Countries
India
Contacts
Public ContactDr Vandana Mehra
All India Institute of Medical Sciences Bhopal
Outcome results
None listed