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A clinical trial to study the effect of two drugs clonidine and dexmedetomidine when mixed with small proportion with bupivacaine( a local anaesthetic) in patients posted for upper limb surgery (shoulder, arm , forearm,hand and fingers)in supraclavicular brachial plexus block (a type of anaesthesia)

A Comparative study of clonidine and dexmedetomidine as an adjunct to bupivacaine in supraclavicular brachial plexus block in patients undergoing elective upper limb surgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/042210
Enrollment
60
Registered
2022-04-27
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: 0.25% Bupivacaine: Amide local anaesthetic Intervention2: NIL: NIL Control Intervention1: CLONIDINE: ALPHA 2 ADRENERGIC AGONIST Control Intervention2: DEXMEDETOMIDINE: ALPHA 2 ADRENERGI

Sponsors

shanti mukand hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Body weight 50-80kg ASA Class 1 and 2 Elective upperlimb surgery of duration 1 to 5 hours

Exclusion criteria

Exclusion criteria: 1)patient not willing for surgery 2)uncooperative patients 3)patients with local pathology at the site of injection 4) history of drug allergy, history of convulsions, bleeding disorder and neurological deficit. 5) ASA CLASS 3 And above.

Design outcomes

Primary

MeasureTime frame
Based on duration of analgesia in two groups.Timepoint: Intraoperatively 1min, 5min ,10 min, 15 min, 30 min, 45 min , 1hr Postoperatively 0 min,15 min,30min,1hr,3hr,6hr,12hr,18hr,24hr—

Secondary

MeasureTime frame
- To compare the incidence of sedation, hypotension, bradycardia and allergic reactions.Timepoint: 60 patients—

Countries

India

Contacts

Public ContactNEELIKA DHILLON

Shanti Mukand Hospital

rajeshdhall12@gmail.com9953220733

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026