Health Condition 1: K721- Chronic hepatic failure
Conditions
Interventions
None listed
Sponsors
Mahatma Gandhi Hospital and Medical College
Eligibility
Inclusion criteria
Inclusion criteria: -Patients with chronic liver disease undergoing liver transplantation -Age group of 18-60 years -Patient with written informed consent
Exclusion criteria
Exclusion criteria: -Patient refusal -Cadaveric donor liver transplantation -Recurrent cardiac arrhythmia -Reduced ventricular systolic function - left (ejection fraction -BMI more than 30 -Intra-operative use of vasopressors or inotropes before or during VTC -Chronic lung disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine efficacy of PPV and SVV changes after tidal volume challenge in predicting fluid responsiveness in a liver transplant recipient under general anaesthesia with lung protective ventilation.Timepoint: Time point- After induction of anaesthesia, the tidal volume Challenge (VTC) test will be performed when patient develop hypotension (fall in Systolic Arterial Pressure 20 % from the baseline / MAP below 65 mm/Hg) prior to administration of fluid bolus or any vasopressor agents. Only the data obtained from the first fluid challenge administered to each enrolled patient will be used for the analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: Not Applicable | — |
Countries
India
Contacts
Public ContactDr Ganesh Ramaji Nimje
Mahatma Gandhi Hospital and Medical College, Jaipur
Outcome results
None listed