Effectiveness of platelet concentrate in non surgical treatment of periodontitis

Evaluation of the effectiveness of adjunctive intra pocket delivery of injectable platelet concentrate (iPRF) in non surgical periodontal therapy-A randomized controlled split mouth trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/042092

Enrollment

100

Registered

2022-04-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Adjunctive intra pocket delivery of iPRF in non surgical periodontal therapy in patients with moderate to severe periodontitis: In addition to the procedures undertaken for control grou

Eligibility

Inclusion criteria

Inclusion criteria: (a) subjects with age more than 18 (b) systemically healthy subjects (c) Patients with at least two sites with probing pocket depth (PPD) = 5 mm on contralateral side either in maxilla or mandible

Exclusion criteria

Exclusion criteria: 1) Subjects with habit of Smoking and tobacco chewing 3) Subjects taking Medications affecting the periodontium 4) Pregnancy or lactation 5) Subjects received probiotic or antimicrobial therapy in the past 6 months 6) Subjects underwent periodontal therapy in the past 6 months

Design outcomes

Primary

Measure	Time frame
Probing pocket depthTimepoint: Final outcome assessed at 6th month after nonsurgical periodontal therapy	—

Secondary

Measure	Time frame
1) clinical attatchment level 2) Gingival recessionTimepoint: Final outcome assessed at 6th month after nonsurgical periodontal therapy	—

Countries

India

Contacts

Public ContactDr Baiju R M

Government Dental College

baijurm@gmail.com9447279605

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026