Health Condition 1: S369- Injury of unspecified intra-abdominal organ
Conditions
Interventions
Intervention1: 24 hour regimen of prophylactic antibiotics in abdominal trauma patients undergoing operative intervention: 24 hours of Intravenous (I.V) INJ CEFOPERAZONE-SULBACTUM 2G TDS alongwith INJ
Sponsors
AIIMS New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.All patients who have sustained abdominal trauma and have underwent operative intervention within 24 hours of injury 2.Hemodynamically stable patients
Exclusion criteria
Exclusion criteria: 1.Patients with age 65 years 2.Patients with associated severe injuries such as open fractures , crushed/mangled extremities, vascular injuries, severe head injury or any other that requires prolonged antibiotic administration 3.Patients with co-morbidities like Hypertension, Diabetes, CKD, CLD, Immunocompromised state and coagulopathic disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the rate of Surgical Site Infection (SSI) between 24 hour and 5 day antibiotic groups in abdominal trauma patients undergoing operative interventionTimepoint: Whenever signs of SSI show up or at 7,14,28 days postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the 30 day mortality between both the antibiotic groupsTimepoint: 30 days;To compare the length of hospital stay between both the antibiotic groupsTimepoint: Till discharge;To compare the rate of non surgical site infections between both the antibiotic groupsTimepoint: Whenever the signs of non surgical site infections show up of at 7,14,28 days postoperatively;To compare the rates of readmission for SSI between both the antibiotic groupsTimepoint: Whenever the patient is readmitted due to SSI | — |
Countries
India
Contacts
Public ContactDamodar Kakumanu
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed