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Comparing efficacy between injecting bupivacaine( drug used for local pain relief) versus hydrocortisone (steroid that can be used for pain relief) inside the abdomen for pain relief after removal of uterus using laparoscopic method( using camera via small cuts made in the abdomen)

COMPARISON OF EFFICACY OF INTRAPERITONEALLY INSTILLED BUPIVACAINE VERSUS HYDROCORTISONE IN LAPAROSCOPIC HYSTERECTOMY FOR POSTOPERATIVE PAIN- A PROSPECTIVE, RANDOMIZED COMPARATIVE STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042078
Enrollment
38
Registered
2022-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 1- Obstetrics

Interventions

Intervention1: Inj Bupivacaine: Patients assigned in this group will receive instillation of 100mg Bupivacaine in 250mL saline into the peritoneum through laproscopic port incision before the insuffla

Sponsors

Rajarajeswari medical college and hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.American society of anesthesiologists physical status 1 and 2 female patients posted for elective laparoscopic hysterectomy 2.Patients undergoing laparoscopic hysterectomy under general anaesthesia. 3.Aged between 20 and 60 years 4.Valid informed/explained consent

Exclusion criteria

Exclusion criteria: 1.Patient refusing to participate in the study. 2.Patient with history of chronic pain. 3.Patient with renal, hepatic or cardiac diseases. 4.Patients on opioids ,MAO inhibitors, benzoodiazipines or steroids. 5.History of alcohol or substance abuse.

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of intraperitoneal instillation of bupivacaine versus intraperitoneal instillation of hydrocortisone in patients undergoing Laparoscopic hysterectomy in providing post operative analgesia for shoulder tip pain and abdominal painTimepoint: It will be evaluated at 0 hour, 1 hour, 2 hour, 4 hour, 6 hour and 12th hour postoperatively

Secondary

MeasureTime frame
1. Post operative analgesic requirements. 2.Frequency of nausea and vomiting. 3.Time taken for starting unassisted ambulation. 4.Duration of hospital stay.Timepoint: at 0 hour, 1 hour, 2 hour, 4 hour, 6 hour and 12th hour postpoeratively. Duration of hospital stay is when the patient is discharged from the hospital in number of days

Countries

India

Contacts

Public ContactSameera halima R

Rajarajeswari medical college and hospital

Sameerahalima610@gmail.com7975152385

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026