A clinical trial to study the comparative effect of two doses of nebulised dexmedetomidine on vital parameters ( Blood pressure and heart Rate) during General anaesthesia in adults

Comparative effect of two doses of nebulised dexmedetomidine on hemodynamic response to laryngoscopy and intubation in adults: A prospective randomized study

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/042063

Enrollment

140

Registered

2022-04-22

Start date

Unknown

Completion date

Unknown

Last updated

2024-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nebulised Dexmedetomidine: Nebulised Dexmedetomidine 1mcg/kg for 15 minutes once before general anaesthesia Control Intervention1: Nebulised Dexmedetomidine: Nebulised Dexmedetomidine 2

Eligibility

Inclusion criteria

Inclusion criteria: 1 The patients of either sex in the age group of 18 to 60 years with American Society of Anesthesiologists Physical Status I and II undergoing elective surgery under general anaesthesia.

Exclusion criteria

Exclusion criteria: 1 Patients who are not giving consent 2 Patients with ASA III and ASA IV 3 Patients with anticipated difficult intubation. 4 Pregnant patient 5 Patient with body mass index > 30 kg/m2

Design outcomes

Primary

Measure	Time frame
To compare the two doses of nebulised dexmedetomidine as premedication on hemodynamic response to laryngoscopy and intubation reflex.Timepoint: 24 weeks	—

Secondary

Measure	Time frame
1. To measure post nebulization sedation 2. To determine the post-op sore throat Timepoint: 3 months	—

Countries

India

Contacts

Public ContactJYOTI KANWAT

AIIMS, Bathinda

gopikanwat@gmail.com8130269487

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026