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Comparison of platelet rich plasma and triamcinolone in patient of osteoarthritis of knee for pain relief.

Comparision of the analgesic effect of intraarticular platelet rich plasma and triamcinolone in patient of osteoarthritis knee - randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042058
Enrollment
40
Registered
2022-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified Health Condition 2: M179- Osteoarthritis of knee, unspecified Health Condition 3: M171- Unilateral primary osteoarthritisof knee Health Condition 4: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: Platelet rich plasma: patients will receive intraarticular injection of 5ml of platelet rich plasma Patient receive one injection PRP and follow up for 3 month Control Intervention1:

Sponsors

Government medical college bhavnagr
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)Grades I , II, III Knee OA according to criteria of American college of rheumatology 2)History of chronic pain > 3 month duration 3)Swelling of knee > 4 month 4)X-ray diagnosis ( Kellgren Lawrence 1 and 2)

Exclusion criteria

Exclusion criteria: 1)Knee joint deformities 2)Acute infection 3)H/o knee surgery 4)H/o diabetes mellitus 5)H/o rheumatoid arthritis, gout H/o severe cardio vascular disorder, 5)haematological disorders, renal disorder Immunodeficiency 6)Patients taking anticoagulants 7)Patients with haemoglobin values of 8)H/o vasovagal shock 9)Pregnant and lactating females 10)H/o corticosteroid consumption within last 3 months

Design outcomes

Primary

MeasureTime frame
1)To compare pain decrement by VAS Score ( Visual analogue score). T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.Timepoint: 1)To compare pain decrement by VAS Score ( Visual analogue score). T2)o compare function and mobility increment and generic health improvement by KOOS score (Knee injury and OA Outcome)(at 6 week) 3)To compare prevention and slowing of the progress of disease by KELLGREN & LAWRENCE Grade (at 3 months ) between two group.—

Secondary

MeasureTime frame
1)To compare analgesic requirement during the study period between two group. 2)To compare need of surgical intervention require during study period Between two group. Timepoint: 3 MONTHS—

Countries

India

Contacts

Public ContactJankiben Panchal

Government Medical College, Bhavnagar

trivedi_lopa@yahoo.in6354517097

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026