Health Condition 1: K041- Necrosis of pulp
Conditions
Interventions
Intervention1: PRF ( Platelet Rich FIbrin) membrane: 10 ml of venous blood centrifuged in test tube at 3000 rpm for 10 minutes. Blood clot and plasma removed . Platelet rich fibrin taken with sterile
Sponsors
Shanmathy B
Eligibility
Inclusion criteria
Inclusion criteria: Patients with no systemic disease, Periodontally healthy individuals, Patients willing for voluntary participation and have signed the informed consent, Patents with good oral hygiene Patients with necrotic immature teeth exhibiting radiographic evidence of open apex without periapical pathology or periapical pathology ( <_10mm).
Exclusion criteria
Exclusion criteria: Patients who are allergic to Ciprofloxacin , Metronidazole or Minocycline, Patient with known systemic diseases, Teeth not conducive for rubber dam isolation, Grossly decayed or fractured teeth, Teeth with periapical radiolucency >10mm, Teeth with internal or External root resorption, Periodontally compromised teeth,Patients with bleeding disorders,Platelet count < 1,50,000/mm3, Pregnant women in view of requirements for radiographs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical ssessment of positive pulp response, abscence of mobility, pain , tenderness to percussion and reduction of periodontal probing depthTimepoint: 3,6,9,12,15,18 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Radiographic assessment of increase in root length , dentin wall thickness and narrowing of canal space, root development and apical end closureTimepoint: 3,6,9,12,15,18 months | — |
Countries
India
Contacts
Public ContactShanmathy B
TamilNadu Government Dental College and Hospital
Outcome results
None listed