Health Condition 1: K045- Chronic apical periodontitis
Conditions
Interventions
Intervention1: Carica Papaya extract: Carica papaya extract as intracanal medicament in apical periodontitis - placed in the root canals during the first visit for 7 days followed by second visit and
Sponsors
Dr Nishitha Arun
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with symptomatic Apical Periodontitis prescribed for 2.Root Canal treatment within the age group of 18-60 years. 3.Permanent single rooted teeth with fully formed apex. 4.Patients should not have taken any analgesic or antibiotic drugs within the previous 7 days.
Exclusion criteria
Exclusion criteria: 1.Patients not willing to sign the informed consent. 2.Patients with variation in root canal morphology. 3.Patients with systemic diseases such as diabetes, central nervous system disorders, cardiovascular disorders, respiratory disorders, immunocompromised patients and pregnant patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expression of Substance P before and after placement of intra canal medicament. Timepoint: 1) first visit after cleaning and shaping of root canal 2) second visit 7 days after the placement of intracanal medicament | — |
Secondary
| Measure | Time frame |
|---|---|
| Expression of Calcitonin Gene Related Peptide (CGRP)Timepoint: 1) first visit after cleaning and shaping of root canal 2) second visit 7 days after the placement of intracanal;Post operative painTimepoint: 1) before commencement of rootcanal treatment 2) 6 hours after the treatment 3) 24 hours after the treatment 4) 48 hours after the treatment 5) 72 hours after the tretment | — |
Countries
India
Contacts
Public ContactDr Sindhu Ramesh
Saveetha Dental College
Outcome results
None listed