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Fluid responsiveness in renal transplant patients after tidal volume challenge test

Assessment of Fluid Responsiveness after Tidal Volume Challenge in Renal Transplant Recipients: A Prospective Observational Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/042038
Enrollment
30
Registered
2022-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N186- End stage renal disease

Interventions

None listed

Sponsors

Mahatma Gandhi Hospital and Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Patients of end-stage renal disease undergoing renal transplantation -Age group of 18-60 years -Patient with written informed consent

Exclusion criteria

Exclusion criteria: -Patient refusal -Cadaveric donor renal transplantation -Recurrent cardiac arrhythmia -Reduced ventricular systolic function - left (ejection fraction -BMI more than 30 -Intra-operative use of vasopressors or inotropes before or during VTC -Chronic lung disease

Design outcomes

Primary

MeasureTime frame
To determine efficacy of PPV and SVV changes after tidal volume challenge in predicting fluid responsiveness in a renal transplant recipient under general anaesthesia with lung protective ventilation.Timepoint: The tidal volume Challenge (TVC) test will be performed when patient develop hypotension (fall in Systolic Arterial Pressure 20 % from the baseline / MAP below 70 mm/Hg) prior to administration of fluid bolus or any vasopressor agents. Only the data obtained from the first fluid challenge administered to each enrolled patient will be used for the analysis.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Ganesh Ramaji Nimje

Mahatma Gandhi Hospital and Medical College, Jaipur

ganesh.nimje8@gmail.com9503332784

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026