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Study to assess whether patients on medicines for epilepsy require less drugs for general anaesthesia

Effect of anti convulsant therapy on dose requirements of anaesthetic agents under general anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/042035
Enrollment
50
Registered
2022-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G40- Epilepsy and recurrent seizures

Interventions

Intervention1: propofol requirement in epileptic patients: dose of propofol required for induction of general anaesthesia in patients who are on anticonvulsant drugs will be noted. Control Interventio

Sponsors

Amrita institute of medical sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patient receiving anticonvulsant therapy for more than one year. Patient undergoing surgery under general anaesthesia . Mallampatti I and II

Exclusion criteria

Exclusion criteria: Allergy to propofol. Emergency procedures . Pregnancy. Patient on rate control medications.

Design outcomes

Primary

MeasureTime frame
dose of propofol required for induction of general anaesthesiaTimepoint: at end of induction of general anaesthesia—

Secondary

MeasureTime frame
dose of intraoperative fentanyl , isoflurane and haemodynamic variablesTimepoint: dose of fentanyl and isoflurane at end of surgery haemodynamic variables 1,3 ,5 minutes after induction and then every 30 minutes—

Countries

India

Contacts

Public ContactDr Gayathri sreekumar

AMRITA INSTITUTE OF MEDICAL SCIENCES

sunilrajan@aims.amrita.edu9447464652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026