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Changes in inflammatory markers following vitamin c supplementation in head and neck cancer surgeries

Modulation of inflammatory markers following Perioperative vitamin c supplementation in head and neck onco surgeries.A prospective randomised trial in a tertiary care centre.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/042012
Enrollment
60
Registered
2022-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx

Interventions

Intervention1: Vitamin c: Injection vitamin c 1 gm once daily will be given in head and neck cancer surgeries from one day prior to surgery till 4 th postoperative day Control Intervention1: normal sa

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA PS I,II patients

Exclusion criteria

Exclusion criteria: Emergency surgeries Pregnancy Re exploration surgeries Mentally challenged patients Patients allergic to vitamin c Renal dysfunction Hepatic dysfunction

Design outcomes

Primary

MeasureTime frame
To compare Interleukin 6 and C reactive protein values between study and control groupTimepoint: Serial measurements of the above From preoperative day till 4 th post operative day—

Secondary

MeasureTime frame
To compare hemodynamic variables and analgesic requirements and overall length of ICU and hospital stayTimepoint: From the day of surgery till discharge of the patient—

Countries

India

Contacts

Public ContactDr Abinash Panigrahi

B.R.A.I.R.C.H.,AIIMS, NEW DELHI

sushmabhatnagar1@gmail.com9811326453

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026