Health Condition 1: B972- Coronavirus as the cause of diseases classified elsewhere Health Condition 2: O- Medical and Surgical
Conditions
Interventions
None listed
Sponsors
AIIMS Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: 1.COVID Positive patients 2.American Society of Anesthesiologist Grade I-III 3.Patient undergoing surgery
Exclusion criteria
Exclusion criteria: 1.Any contraindication to general anesthesia/regional/spinal anaesthesia 2.Patients on recent chemotherapy/radiotherapy(past 15 days). 4.Patient on chronic treatment with steroids or immune-suppressants. 5.Patient who are morbidly obese, have autoimmune disorders. 6.Patient underwent blood transfusion for 7.Patients not willing to give consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Difference in biochemical and hematological markers (complete blood count, IL-6) at three time points (preoperatively, immediately and 24hours after the end of the surgery) in COVID positive/suspect patients undergoing major surgeryTimepoint: Baseline At end of surgery 24 hours post surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Early mortality- within same hospital admission/within one month, whichever is earlierTimepoint: one month;Major morbidity- Surgical site infection, Need for post-operative ventilation and its duration, need for BIPAP support, Duration of ventilation, inotropic score, ICU stay, length of hospital stayTimepoint: peri-operative;Perioperative adverse events- hypotension, hypoxia, apnea, bradycardia and cardiac arrest.Timepoint: Perioperative | — |
Countries
India
Contacts
Public ContactDr Ajit Kumar
AIIMS Rishikesh
Outcome results
None listed