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to observe changes in Internal carotid artery and optic nerve sheath diameter after induction of general anaestheisa, carbon dioxide insufllation and head up tilt in patients undergoing laparoscopic cholecystectomy under general anaesthesia to predict and prevent changes in Intra-cranial pressure.

Internal carotid artery blood flow and optic nerve sheath diameter response to anaesthesia, pneumoperitoneum and head up tilt during laparoscopic cholecystectomy under general anaesthesia : a clinical study.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2022/04/041974
Enrollment
35
Registered
2022-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

None listed

Sponsors

Mahtma Gandhi Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Consenting patients of either sex undergoing elective laparoscopic Cholecystectomy under general anaesthesia. 2. Age 18-60 yrs. 3. Non obese patients (BMI equal to or less than 32kg/m2). 4. Patient belonging to physical status ASA grade I/II.

Exclusion criteria

Exclusion criteria: 1. Patients falling in criteria but not giving consent to participate in the study. 2. ASA grade III/IV/V. 3. Patient with hyperlipidaemia, known coronary artery disease, hypertension, cerebrovascular disease, diabetes mellitus, Patients on beta blockers or on statin therapy.

Design outcomes

Primary

MeasureTime frame
To derive and study changes in internal carotid artery blood flow ultrasonographically in patients undergoing elective laparoscopic cholecystectomy under general anaesthesia in terms of internal carotid artery diameter, internal carotid artery velocityTimepoint: 1. before induction of anaesthesia 2. 2 minutes after induction of anaesthesia 3. 2 minutes after creation of pneumoperitoneum 4. 2 minutes after head-up tilt—

Secondary

MeasureTime frame
1- To relate these changes with changes in Optic nerve sheath diameter (ONSD). 2- To relate these changes in internal carotid artery blood flow to mean arterial pressure, end tidal carbon dioxide (EtCO2). Timepoint: 1- Awake - just before induction of anaesthesia. 2- Two minutes after induction of anaesthesia, 3- Two minutes after creation of pneumoperitoneum and 4- Two minutes after providing head up tilt—

Countries

India

Contacts

Public ContactDr Shubhina gupta

Mahtama Gandhi University of Medical Sciences and Technology

avnishbharadwaj1@gmail.com9314882845

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026