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A clinical trial to study the Effectiveness of Topical Tranexamic Acid in controlling Anterior Nasal Bleeding.

Effectiveness of Topical Tranexamic Acid in Anterior Epistaxis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/041922
Enrollment
184
Registered
2022-04-19
Start date
Unknown
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R040- Epistaxis

Interventions

Intervention1: Tranexamic acid Injection 500mg/5ml : Topical application of injectable form of Tranexamic acid 500mg/5ml by placing 10cm cotton pledget soaked in the drug for 10 mins in nasal cavity

Sponsors

DrSoujanya Balaraj
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adult males or females presenting to ENT and Emergency Department with active anterior nasal bleeding not resolved with simple first aid measures

Exclusion criteria

Exclusion criteria: Patients with Visible bleeding vessel ,Lack of consent, Posterior nasal bleeding, Shock defined as systolic blood pressure of 90 mmHg or diastolic blood pressure of 60 mmHg, tachycardia defined as greater than 100beats per min, Major Traumatic nasal bleeding ,on Anticoagulation therapy, known Bleeding disorder, Pregnant women.

Design outcomes

Primary

MeasureTime frame
Effectiveness of Topical Tranexamic Acid to control Anterior EpistaxisTimepoint: Within 10 minutes calculated in percentage

Secondary

MeasureTime frame
Proportion of patients who required rescue treatment that is anterior nasal packing. Proportion of patients who had re-bleeding Length of hospital stay Patient satisfaction Timepoint: After using tranexamic acid topically for 10 mins calculated in percentage. Within first 24 hours and 7 days after intervention. Calculated in hours from time of entry to exit from hospital. 0-5 numeric rating scale.

Countries

India

Contacts

Public ContactDrSoujanya Balaraj

Ramaiah Medical College

soujanya_balaraj@yahoo.co.in9980821610

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026