Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Dexmedetomidine: To compare intravenous dexmedetomidine 0.25mcg/kg with intravenous lignocaine 1.5mg/kg.
Intervention2: Dexmedetomidine: To compare intravenous dexmedetomidine 0.5mcg/kg
Sponsors
Pt B D Sharma PGIMS Rohtak
Eligibility
Inclusion criteria
Inclusion criteria: ASA Grade I and II patients of either sex in age group of 16 -65 years posted for surgery under General Anaesthesia after an informed and written consent.
Exclusion criteria
Exclusion criteria: Patients having anticipated difficult intubation patients having oropharyngeal pathology patients with a history of cardiovascular problems patients on sedative hypnotics and antidepressants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Haemodynamic response will be compared in between groups by measuring Heart rate systolic blood pressure diastolic blood pressure mean arterial pressure oxygen saturation ECG will be recorded throughout the procedure however any event of dysrhythmias will be notedTimepoint: Baseline before the drug was given B1 Just before laryngoscopy B2 Just before intubation T0 1minute after intubation T1 3minute after intubation T3 5minute after intubation T5 | — |
Secondary
| Measure | Time frame |
|---|---|
| Bradycardia Hypotension Sedation Post operative nausea and vomiting PONVTimepoint: Intraoperative bradycardia Intraoperative hypotension Post operatively sedation PONV | — |
Countries
India
Contacts
Public ContactDr Ankit Tyagi
Pt. B. D.Sharma ,PGIMS ,Rohtak
Outcome results
None listed