Comparing organic bone replacement material from egg shell with man-made materials in rate of bone healing after lower wisdom tooth removal

Comparative evaluation of egg shell derived Nano hydroxyapatite and synthetic hydroxyapatite both combined with concentrated growth factor in bone regeneration after mandibular 3rd molar surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/041859

Enrollment

Registered

2022-04-13

Start date

Unknown

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Egg shell derived hydroxyapatite: Chicken egg shell, sterilised and ground into powder. Concentrated growth factors Mix will be packed into extraction at socket at time of surgery (sin

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing bilateral mandibular 3rd molar extraction 2. Patients with no associated pathologies and medical conditions or any medications that might alter the healing potential - ASA 1 and ASA 2

Exclusion criteria

Exclusion criteria: 1. Medically compromised patients 2. Patients with unilateral impacted lower third molars 3. Patients on preoperative anti-inflammatory medication 4. History of systemic diseases 5. Pregnant patients

Design outcomes

Primary

Measure	Time frame
1. Bone regeneration: Verified using CBCT Timepoint: 1. 1 month, 3 months, 6 months	—

Secondary

Measure	Time frame
Wound healing - clinical examinationTimepoint: 1 month	—

Countries

India

Contacts

Public ContactProf Dr Senthilnathan

Saveetha Dental College and Hospitals

dr.nathankps@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026