Local application of multifunctional cocktail is lumbar spine surgery

To study the effect of a locally administered multifunctional cocktail on postoperative pain and blood loss in elective lumbar spinal surgeries: A prospective randomized control trial.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/041828

Enrollment

Registered

2022-04-12

Start date

Unknown

Completion date

Unknown

Last updated

2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M95-M95- Other disorders of the musculoskeletal system and connective tissue

Interventions

Intervention1: LOCAL APPLICATION OF MUTODRUNG MULTIFUNCTIONAL COCKTAIL OF TRANEXAMIC ACID,ROPIVACAINE AND METHYLPREDNISOLONE: The surgery will be performed as per standard protocol. At the time of clo

Eligibility

Inclusion criteria

Inclusion criteria: 1) Age of patient 18 -80 years. 2) Patient undergoing elective lumbar spinal surgery for an extradural pathology. 3) Patients who provide informed written consent for participation in the study

Exclusion criteria

Exclusion criteria: (1) Intradural pathologies (2) Pathologies involving the cervical spine and thoracic spine (3) History of any psychiatric illness in the patient (4) Patients with severe respiratory cardiac, hepatic or renal dysfunction (5) Patients who have undergone a previous lumbar spine surgery. (6) History of allergy to any of the drugs being used in the cocktail. (7) Patients with ASA grade of more than 3. (8) Patients who are on antiplatelet drugs like aspirin and anticoagulants (9) Patients with previous history of thromboembolism.

Design outcomes

Primary

Measure	Time frame
To compare opioid requirement at the end of 48 hours between the two groups Timepoint: end of 48 hours	—

Secondary

Measure	Time frame
TO COMPARE BLOOD LOSS AND HEMATOCRIT OF DRAIN FLUIDTimepoint: 24/48HRS/TILL DRAIN REMOVAL	—

Countries

India

Contacts

Public ContactDr SACHIN ANIL BORKAR

AIIMS NEW DELHI

SACHIN.AIIMS@GMAIL.COM9968859645

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026