Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Goal directed therapy: Goal directed therapy algorithm
(During the total intra-operative period)
Control Intervention1: Standard fluid therapy group: Clinical experience based on hemod
Sponsors
Department of Neuroanaesthesia Critical Care
Eligibility
Inclusion criteria
Inclusion criteria: 1) Patient aged > 18 years. 2) American Society of Anaesthesiologist (ASA) physical status 1 and 2. 3) World Federation of Neurologic Surgeons (WFNS) grade I to II aSAH and who were scheduled for an endovascular therapeutic procedure for aSAH under general anaesthesia within 5 days of aneurysm rupture.
Exclusion criteria
Exclusion criteria: 1) Patient refusal 2) Patient aged 3) Pregnant women 4) American Society of Anaesthesiologist (ASA) physical status 3 and above. 5) World Federation of Neurologic Surgeons (WFNS) grade III and above aSAH and who were scheduled for an endovascular therapeutic procedure for aSAH under general anaesthesia beyond 5 days of aneurysm rupture. 6) An unruptured aneurysm(s) or did not have aSAH. 7) A previous clipping or coiling procedure for the same aneurysm. 8) Undergone a concomitant extracranial-intracranial bypass procedure or other non-neurosurgical procedure. 9) Patient allergic to medications
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total duration of hypovolemia.Timepoint: At the end of procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Total duration of hypotension 2)Incidence of dehydration just before induction of anesthesia. 3)Volume of fluid infused. 4)Incidence of vasospasm. 5)Incidence of delayed cerebral ischemia (DCI). 6)Duration of ICU stay 7)Duration of hospital stay 8)Neurological outcome at discharge 9)Incidence of post-operative complications till discharge - cardiac, pulmonary and other systemic complications. Timepoint: Before induction, at the end of procedure, during hospital stay and at discharge | — |
Countries
India
Contacts
Public ContactSaurav Singh
AIIMS New Delhi
Outcome results
None listed