Health Condition 1: R69- Illness, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Age >18 years. 2)Requiring invasive mechanical ventilation at ICU admission. 3)Expected duration of mechanical ventilation >72 hours. 4)Ready to undergo spontaneous breathing trial
Exclusion criteria
Exclusion criteria: Past history of neuromuscular disorders Mechanical ventilation >48 hrs within current hospital admission Obesity (BMI >35) Pregnant women Abdominal wound at proposed location of ultrasound probe due to recent abdominal surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abdominal expiratory muscle thickness as a predictor of successful weaning in ready to wean critically ill patients receiving mechanical ventilation.Timepoint: At admission At 72 hours Just before Spontaneous breathing trial in ready to wean patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between change in expiratory muscle and diaphragmatic thickness in critically ill patients receiving mechanical ventilation.Timepoint: At admission At 72 hours Just before Spontaneous breathing trial in ready to wean patients;Factors predicting change in abdominal expiratory muscle thickness in critically ill mechanically ventilated patients.Timepoint: During ICU stay;To assess time dependent changes of expiratory muscle thickness in critically ill mechanically ventilated patientsTimepoint: At admission At 72 hours Just before Spontaneous breathing trial in ready to wean patients | — |
Countries
India
Contacts
All India institute of medical sciences, Rishikesh