A clinical study to compare the effects of nitrofurantoin and extract form of Unani drugs in the treatment of E.coli induced Urinary Tract Infection.

A Clinical Study on the Management of E.coli induced Urinary Tract Infection (Tadiya-e-Majra-e-Baul) with A Unani Polyherbal Formulation, A Randomized Standard Controlled Trial.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/04/041663

Enrollment

Registered

2022-04-05

Start date

Unknown

Completion date

Unknown

Last updated

2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N390- Urinary tract infection, site notspecified

Interventions

Intervention1: Extract of Unani polyherbal formulation- Khar-khask (Tribulus terrestris) Bhuiamla (Phyllanthus niruri) Kababcheeni (Piper cubeba) Beekh -eKasni (Cichorium intybus) Beekh-ekarafs (Apium

Eligibility

Inclusion criteria

Inclusion criteria: Patient between the age of 18 to 65 years of either sex. Diagnosed patient of E. coli induced UTI (by urine culture & sensitivity). Patients willing to participate and sign the understood, informed consent form. Patient willing to discontinue the drugs taking for the treatment of UTI.

Exclusion criteria

Exclusion criteria: Patients with any anatomical abnormality of urinary tract. Patient with Diabetes Mellitus. Patient with Hepatic & Renal insufficiency and malignancy. Pregnant and lactating women. Resistant to the standard control drug Patient unwilling to sign the consent form.

Design outcomes

Primary

Measure	Time frame
To develop a safe efficacious and cost effective drug from a herbal source for the management of Urinary Tract Infection Tadiya e Majra e Baul caused by E coli To evaluate the safety and efficacy of the proposed Unani Polyherbal Formulation in the treatment of Urinary Tract Infection Tadiya e Majra e Baul caused by E coli To compare the results of polyherbal unani formulation from standard control drug in respect of safety and efficacy in the treatment of UTI Timepoint: 30 Days	—

Measure

Time frame

To develop a safe efficacious and cost effective drug from a herbal source for the management of Urinary Tract Infection Tadiya e Majra e Baul caused by E coli To evaluate the safety and efficacy of the proposed Unani Polyherbal Formulation in the treatment of Urinary Tract Infection Tadiya e Majra e Baul caused by E coli To compare the results of polyherbal unani formulation from standard control drug in respect of safety and efficacy in the treatment of UTI Timepoint: 30 Days

—

Secondary

Measure	Time frame
To evaluate the improvement of quality of life in test group patientsTimepoint: 30 Days	—

Countries

India

Contacts

Public ContactDr Shahala Anjum

Ayurvedic and Unani Tibbia College and Hospital

drrahman002@gmail.com9313980776

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026