Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Tranexamic acid,
Hemocoagulase: Intravenous administration of Tranexamic acid 15mg/kg 30 minutes before surgery.
Intraoperative local application of Hemocoagulase solution 4drops/cm2 of
Sponsors
Harshit Verma
Eligibility
Inclusion criteria
Inclusion criteria: All breast cancer patients who will undergo axillary lymph node dissection.
Exclusion criteria
Exclusion criteria: Patient who has received prior radiation therapy to the axilla. Patients with history of known allergy to drugs used. Patients who are known case of clotting disorder or active thromboembolic disease. Patients pregnant or lactating. Patients with past or current history of lymphedema of limb on the affected side. Patients not willing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To measure and compare the cumulative axillary drain output in breast cancer patients undergoing axillary lymph node dissection treated with Tranexamic acid plus Hemocoagulase versus placebo.Timepoint: 30 days | — |
Secondary
| Measure | Time frame |
|---|---|
| Days after axillary drain is removedTimepoint: Till axillary drain is in situ;Frequency and volume of axillary seroma aspirationsTimepoint: till 30 days from surgery;Incidence of surgical site infectionTimepoint: till 30 days from surgery | — |
Countries
India
Contacts
Public ContactHarshit Verma
All India Institute of Medical Sciences, Patna
Outcome results
None listed