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Effect of Arginine containing toothpaste on dental decay causing enzyme levels in oral cavity

Effect of arginine-containing toothpaste on glycosyltransferase levels in dental plaque in adolescent school children- A Randomised Controlled Clinical Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/04/041593
Enrollment
40
Registered
2022-04-01
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K029- Dental caries, unspecified Health Condition 2: B999- Unspecified infectious disease

Interventions

Intervention1: Arginine: Arginine is an semi-essential amino acid. it has anti-caries action and remineralising potential. Arginine containing toothpaste for 1 year Control Intervention1: Fluoride: Fl

Sponsors

Astha Bramhecha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: children in the age group of 11-13 years Participants available during the duration of study.

Exclusion criteria

Exclusion criteria: Children with presence/frequent use of any intra-oral appliance Children with physical disability Children on long term oral medication Children having systemic illness

Design outcomes

Primary

MeasureTime frame
Levels of Glycosyltransferase enzyme in dental plaque and salivaTimepoint: Levels of Glycosyltransferase enzyme in dental plaque and saliva at baseline, 6 months and 12 months—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactAstha Bramhecha

Saveetha Dental College

krithikadatta.sdc@saveetha.com9840111369

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026