Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sevoflurane: Patient will be induced using 8% Sevoflurane in 50% Nitrous Oxide and oxygen at 3L/min at induction till attaining a MAC of 1.8 to 2 and maintained using Sevoflurane 2-3 %
Sponsors
All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age between 3 -I0 years 2.Patients undergoing pediatric procedures under GA 3.ASA grade I and II 4.Consent from parents 5.Can be either males or females
Exclusion criteria
Exclusion criteria: 1.Refusal to consent 2.History of perinatal hypoxia/ preterm delivery 3.History of seizure disorders 4.History of developmental disorder 5.History of any psychiatric illness 6.Any electrolyte imbalance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Correlate the changes in fNIRS recordings with sevoflurane and propofol in the frontal cortex of children of 3 ? 10 years undergoing pediatric proceduresTimepoint: 1. Baseline fNIRS reading before induction 2.fNIRS reading for 5 minutes after securing the airway with LMA/ETT 3.fNIRS reading for 5 minutes at the end of the procedure after stopping the anaesthetic agent | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of emergence delirium in sevoflurane versus propofol total intravenous anaesthesia as assessed by the PAED scale, evaluating postoperative pain using CHEOPS , and postoperative delirium assessment using CORNELL scoreTimepoint: PAED Score is recorded during 5 min intervals till 30 minutes from the time of awakening. Postoperative pain is assessed using CHEOP score , measured every I0 min intervals till 30min from awakening Patient is assessed for postoperative delirium using CAPD at the end of 2 hours. | — |
Countries
India
Contacts
Public ContactDr Kavya V Nair
All India Institute of Medical Sciences , New Delhi
Outcome results
None listed