Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Intermittent Inflow Occlusion [IIO] technique by Pringle Maneuver during robotic donor hepatectomy using right hemiliver grafts: Each IIO procedure consisted of clamping of the hepatodu
Sponsors
Amrita Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: All prospective male and female liver donors between 18 - 60 years of age admitted for live donor liver transplantation with right hemiliver grafts using robotic donor hepatectomy
Exclusion criteria
Exclusion criteria: (1) Prospective donors who denied consent (2) Prospective donors of recipients with fulminant hepatic failure before liver transplantation (3) Prospective donors for ABO-incompatible liver transplant (4) Prospective donors of recipients who has undergone organ transplantation previously (5) Prospective donors of recipients who are scheduled to undergo multi organ transplantation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the blood loss during Robotic Donor Hepatectomy with and without Intermittent Inflow Occlusion [IIO] by Pringle maneuver in adult living donor liver transplantation using right hemiliver graftsTimepoint: At the end of donor surgery [Robotic Donor Hepatectomy using right hemiliver grafts] | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood transfusion requirements in donorTimepoint: During both intraoperative and postoperative period - upto the day of discharge from hospital;Early graft dysfunction incidenceTimepoint: Within 2 weeks from the date of liver transplantation;Hospital stay in donorTimepoint: Number of days - will be noted at the time of discharge;ICU stay in donorTimepoint: Number of days - will be noted at the time of shift from ICU to ward / room;Peak ALT level in donor within 7 days after surgeryTimepoint: Within 7 days after surgery;Peak ALT level in recipient within 7 days after surgeryTimepoint: Within 7 days after surgery;Peak Bilirubin level in donor within 7 days after surgeryTimepoint: Within 7 days after surgery;Peak INR level in donor within 7 days after surgeryTimepoint: Within 7 days after surgery;Peri-operative morbidity and mortality in recipient [within 30 days from date of transplantation]Timepoint: Within 30 days from the date of liver transplantation;Skin incision to graft out time in donor surgeryTimepoint: Data will be collected during the surgery;Time taken from beginning of parenchymal transection to hepatic vein looping in donor surgeryTimepoint: Data will be collected during the surgery;Total duration of donor surgeryTimepoint: Data will be collected at the end of the surgery;Warm ischemia and Cold ischemia time of graftTimepoint: Data will be collected at the end of the surgery | — |
Countries
India
Contacts
Public ContactDr Rahul D Kunju
Amrita Institute of Medical Sciences Cochin, Kerala
Outcome results
None listed