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Effect of preoperative administration of Dexamethasone for postoperative pain.

The effect of preoperative administration of Dexamethasone for postoperative pain in patients undergoing Laproscopic Cholecystectomy under General Anaesthesia.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041519
Enrollment
80
Registered
2022-03-31
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K802- Calculus of gallbladder without cholecystitis

Interventions

Intervention1: inj. dexamethasone 8mg iv versus inj NS 2ml iv as placebo: inj. Dexamethasone 8mg i/v given slowly over a period of 5 minutes one hour prior to induction of GA in patients undergoing L

Sponsors

Dr Savneet Sasan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA grade I & II 2. Body Weight between 45 to 90 kg & BMI between 18 to 30kg / m sq. 3. Scheduled for Elective Laproscopic Cholecystectomy.

Exclusion criteria

Exclusion criteria: 1. patient refusal 2. ASA 3 & 4 3. Hepatic & renal insufficiency 4. Previous gastric ukcers, diabetes mellitus 5. Pregnant & Nursing mothers 6. History of corticosteroid hypersensitivity. 7. Patients already on corticosteroids , immunosuppressives , analgesics or opioid medication. 8. Emergency Surgery 9. Inability to understand & use the VAS 10. Chronic pain syndrome

Design outcomes

Primary

MeasureTime frame
To evaluate the post-operative pain relief efficacy of preoperatively administered Dexamethasone when given in a dose of 8mg by intravenous route one hour prior to induction of General Anaesthesia in patients undergoing Laproscopic Cholecystectomy as assessed by Visual Analogue Score.Timepoint: 6 months

Secondary

MeasureTime frame
1 Time to first rescue analgesia 2 Number of doses of the rescue analgesia used in 24 hours. 3 Postoperative hemodynamic parameters 4. Study the adverse effects of drug ( if any). 5. Time to hospital discharge in hoursTimepoint: 6 months

Countries

India

Contacts

Public ContactDr Sunana Gupta

ASCOMS hospital

sunaynaarnav@yahoo.com9419160705

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026