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Comparing two medications plain bupivicaine and bupivicaine with dexamethasone for their effect on maintaining blood pressure in brain surgeries.

Comparision of Plain Bupivicaine with Bupivicaine plus Dexamethasone in Scalp nerve blocks in patients undergoing Supratentorial Craniotomy under General Anesthesia: A Prospective Randomised Clinical Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041500
Enrollment
140
Registered
2022-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Plain bupivicaine local: Bupivicaine local 0.25% of 10cc drug and dexamethasone 8mg of 2cc drug administered via local skin infiltration method at various nerve levels using 24 1/2 need

Sponsors

Government medical College Baroda
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA – I/II/III. 2.Malampatti Grade- I / II /III 3.Patients diagnosed with intracranial space-occupying lesions scheduled for elective supratentorial cranial surgeries and Craniotomy surgeries. 4.Pre-operative GCS 15/15 5.Patient able to give written & informed consent. 6. Patient able to understand VAS regarding assessment of pain

Exclusion criteria

Exclusion criteria: 1.Patient not willing for procedure. 2.Patients having uncontrolled Diabetes, Hypertension, Liver and Kidney disorders. 3.Pregnant patients. 4.Hypersensitivity to any local anesthetic drug or drugs used in this study. 5.Patients with significant h/o drug or alcohol abuse, psychiatric illness. 6.Patients with scalp infection.

Design outcomes

Primary

MeasureTime frame
Primary outcome to maintain hemodynamic stability (Blood pressure and Heart rate in normal limits)Timepoint: Throught surgery

Secondary

MeasureTime frame
To compare intra-operative requirement of Inj.Fentanyl. Requirement of rescue analgesia in post-op period.Timepoint: Immediate post-op, 30min, 1hr,2hr,4hr,6hr,8hr,12hr,16hr,20hr,24hr

Countries

India

Contacts

Public ContactAravind Kalaimani

Government Medical College, Baroda

drswatibhatt2015@yahoo.com9879372038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026