Health Condition 1: 1- Obstetrics Health Condition 2: 1- Obstetrics Health Condition 3: 1- Obstetrics Health Condition 4: O00-O9A- Pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Granisetron: Intravenous Granisetron 1 milligram injected over one minute. Patients will receive the allocated solution intravenously 5 minutes before spinal anaesthesia.
Control Inter
Sponsors
Dr Jagannath Mishra
Dr Amiya Kumar Nayak
Eligibility
Inclusion criteria
Inclusion criteria: Obstetric patients of American society of Anaesthesiology physical status I/II, between 18 and 40 years of age, at 37-42weeks of gestation and undergoing an elective, lower segment caesarean section (CS) for singleton pregnency are included
Exclusion criteria
Exclusion criteria: Parturients not willing to participate in this study Presence of any contraindication for spinal anaesthesia History of allergy to study drug Patients on selective serotonin reuptake inhibitors or migraine medications Ischemic heart disease cardiac insufficiency Diabetes melliutus chronic hypertension Pregnancy induced hypertension Placenta previa Abnormal fetal development Body mass index >35kg/ sq mt Height Patients with pre-existing QT prolongation or any cardiac conduction abnormality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| attenuation of hypotensionTimepoint: within 45 minutes of administering spinal anaesthesia | — |
Secondary
| Measure | Time frame |
|---|---|
| prevention of bradycardiaTimepoint: within 1 hour of administering spinal anaesthesia | — |
Countries
India
Contacts
Public ContactDr JAGANNATH MISHRA
PRM Medical college and Hospital
Outcome results
None listed