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Administrative of inj.lornoxicam(NSAID) to reduce the incidence of increase in heart rate and blood pressure during laryngoscopy and endotracheal intubation

EFFICACY OF PREOPERATIVE INTRAVENOUS LORNOXICAM ON ATTENUATING THE HEMODYNAMIC RESPONSES FOLLOWING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041484
Enrollment
40
Registered
2022-03-30
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.lornoxicam: Baseline line vitals will be noted before giving the study drugs .The patients will receive i.v. lornoxicam16mg diluted to 4ml in 5ml syringe ,30 mins before endotrachea

Sponsors

CSMAKSHAYA
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients aged between 18 years to 60 years scheduled for elective surgeries under general anaesthesia 2)ASA 1&2

Exclusion criteria

Exclusion criteria: 1)Patients who are allergic to NSAIDS 2)Patients refusal to consent 3)Patients with severe hepatic and renal dysfunction, pregnancy and lactation 4)Patients with a known case of acid peptic ulceration and recurrent peptic ulceration 5) Bleeding disorders and coagulation disorders 6) History of thrombocytopenia, gastrointestinal bleeding, cerebrovascular bleeding 7) Severe cardiac failure

Design outcomes

Primary

MeasureTime frame
To determine the effect of i.v.lornoxicam in attenuation of hemodynamic responses during laryngoscopy and endotracheal intubationTimepoint: Heart rate and blood pressure will be monitored every minute for the first five minutes after laryngoscopy and endotracheal intubation—

Secondary

MeasureTime frame
To determine the side effects of intravenous lornoxicamTimepoint: 24 hrs post-operatively—

Countries

India

Contacts

Public ContactCSMAKSHAYA

DR BR AMBEDKAR MEDICAL COLLEGE

drsalim_iqbal@yahoo.co.in9025751661

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026