Health Condition 1: P220- Respiratory distress syndrome of newborn
Conditions
Interventions
Intervention1: Fentanyl administration during Less Invasive Surfactant Administration: Patients having RDS who required FiO2 more than 30 % on Noninvasive positive pressure ventilation to maintain SpO
Sponsors
IPGMER SSKM HOSPITAL
Eligibility
Inclusion criteria
Inclusion criteria: Preterm baby with gestational age between 28 to 34 weeks diagnosed with RDS will enroll in this study . RDS will be diagnosed clinically initially and later confirm by chest X ray . A written informed consent will be obtained from the parents of the baby for participation in the study
Exclusion criteria
Exclusion criteria: Baby with major congenital anomaly . Perinatal asphyxia (cord blood pH Intubated at delivery room. Alternative cause of respiratory distress.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the need for mechanical ventilation from the LISA procedure onwards up to 72 h of life.Timepoint: The primary outcome is the need for mechanical ventilation from the LISA procedure onwards up to 72 h of life. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of laryngoscopy attempts during the procedure Complications occurring during and after the procedure SpO2 80 percentage hypotension with mean below gestational age bradycardia 100 bpm Incidence of hsPDA IVH above grade3 Broncho Pulmonary Dysplasia Retinopathy of Prematurity requiring treatment Culture positive sepsis Necrotizing Enterocolitis above stage 3 Rate of feed intolerance Gastrointestinal perforation confirmed on roentgenogram or surgical exploration Timepoint: 3month | — |
Countries
India
Contacts
Public ContactDr Bijan Saha
Institute of PostGraduate Medical Education and Research and SSKM Hospital
Outcome results
None listed