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Bupivacaine for Subarachnoid block either premixed with Fentanyl or administered before of after it.

Subarachnoid block characteristics following coadministration of Fentanyl premixed with hyperbaric Bupivacaine versus antecedent or succedent to hyperbaric Bupivacaine. A randomised controlled study.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041442
Enrollment
160
Registered
2022-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2023-02-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: Bupivacaine: Patients will receive 3.0 ml (125mg) of 0.5% hyperbaric bupivacaine in a 5.0 ml syringe once as bolus in subarachnoid block. Control Intervention2: Bupivacaine foll

Sponsors

Mahatma Gandhi Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for elective lower limb surgeries under subarachnoid block. 2.Patients weighing 50 to 70 kgs. 3.Patient under ASA CLASS I/ II /III. 4.Patientâ??s with written and informed consent.

Exclusion criteria

Exclusion criteria: 1.Patient belonging to ASA CLASS IV & V. 2.Patients allergic to the study drugs.

Design outcomes

Primary

MeasureTime frame
To study the Onset and Duration of Sensory and Motor block in minutes. To study the variation in Systolic and Diastolic BP, Mean Arterial Pressure, Heart Rate, Respiratory Rate, SPO2.Timepoint: Intraoperative

Secondary

MeasureTime frame
1.To assess the need of rescue postoperative analgesia in next 24 hr. 2.To study the postoperative side effects viz Nausea, vomiting, Itching, Urinary retention, respiratory depression etc. Timepoint: Postoperative

Countries

India

Contacts

Public ContactDr Avnish Bharadwaj

Mahatma Gandhi University Of Medical Sciences and technology

avnishbharadwaj1@gmail.com9314882845

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026