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Role of Tapentadol Nasal Spray for Pain Relief during and after Operation.

"EFFECTIVENESS OF NASAL APPLICATION OF TAPENTADOL IN PERI OPERATIVE ANALGESIA:PROSPECTIVE COMPARATIVE STUDY"

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041437
Enrollment
54
Registered
2022-03-29
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: TAPENTADOL NASAL SPRAY: Tapentadol Nasal Spray 2 Puffs(25 MG/Puff)-10 minute before induction of anaesthesia. Control Intervention1: PARACETAMOL: Intra Venous Paracetamol 100ml(1gm) ove

Sponsors

Ramakrishna Mission Seva PratishthanVIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA Grade I and II; Elective Laparoscopic Cholecystectomies done under general anaesthesia of minimum 90 mins to less than or equal to 120 mins duration

Exclusion criteria

Exclusion criteria: - Body weight 60 kg; - Known hypersensitivity to any one of the test drugs of the study; - With coagulopathyies or on anticoagulant drugs; - Patient already taking MAO inhibitor or SSRIs; - Taking opioid drugs or other analgesic drugs for any ailment; - Pregnant and lactating women; - Patients having atrophic rhinitis or other nasal pathology.

Design outcomes

Primary

MeasureTime frame
Pain Relief -with the help of various pain scales.Timepoint: POST OPERATIVE 1ST WEEK—

Secondary

MeasureTime frame
Immediate: Hemodynamic stability, CNS depression. Delayed: NA Timepoint: Immediate post operative period(2-3 days). Long term Mortality Not indicated as this study is of short period.—

Countries

India

Contacts

Public ContactDR KEYA CHAKRABORTY

RAMAKRISHNA MISSION SEVA PRATISHTHAN,VIMS

drsanjoymb@gmail.com9830031519

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026