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Comparison of two different solutions in wound healing after tooth extraction

Comparison of local application of hemocoagulase solution and saline pressure pack in wound healing and incidence of dry socket after extraction of mandible first and second molars

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041433
Enrollment
50
Registered
2022-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Hemocoagulase solution: Reduces bleeding time, promotes wound healing and adequate hemostasis. It will be applied once immediately after extraction Control Intervention1: Saline pressur

Sponsors

Dr Kavya Chandra
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients medically fit for extraction under local anaesthesia and patients with no developmental disorders 2)Patients requiring bilateral extraction of mandibular first and second molars  3)Patients without any local pathology like cyst, tumors, generalized jaw bone or systemic diseases interfering with or influencing haemorrhage, clotting or wound healing. 4)Patients with consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1)Patients with known premorbid conditions like thromboembolic disorders, hypertension, haemophilia, diabetes mellitus, anticoagulant therapy 2)Pregnant and lactating patients 3)Hypersensitivity to hemocoagulase topical solution and other constituents of the formulation  4)Patients with mental illness. 5)Patients not willing to participate.

Design outcomes

Primary

MeasureTime frame
Clinical wound healingTimepoint: From application of solution after extraction to 1 week

Secondary

MeasureTime frame
Bleeding stoppage timeTimepoint: from application of solution into the socket or surgical site up to the complete stoppage of bleeding;Complication and side effectTimepoint: From application of solution in site to 1 week postoperatively;Post operative pain and swellingTimepoint: From application of solution in site to two and six hours

Countries

India

Contacts

Public ContactDr S Mohan

Government dental college, KOTTAYAM

Mohanminaram@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026