Efficacy of mouthwash containing Achyranthes aspera and Trachyspermum ammi in the reduction of gingivitis in children

Comparative evaluation of combination of mouthwash containing Achyranthes aspera and Trachyspermum ammi with chlorhexidine mouthwash as an adjunct to oral prophylaxis in children with gingivitis: A double-blind randomized controlled trial

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041423

Enrollment

108

Registered

2022-03-28

Start date

Unknown

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: Mouthwash containing Achyranthes aspera and Trachyspermum ammi (1:2): To be used as a mouthwash 4 ml twice daily, morning and night, 30 minutes after brushing, swish for a full 30 secon

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children diagnosed with mild to moderate type of gingivitis. 2. Children and parents/guardians who are willing to give written consent.

Exclusion criteria

Exclusion criteria: 1. Children with any other systemic/psychological conditions. 2. Children with any history of allergy reactions to herbal medicaments or chlorhexidine. 3. Children under other medications such as anti-inflammatory drugs, antibiotics, and steroids within the past 3 months. 4. Children using any type of antibacterial mouth rinse within four weeks of commencement of the study. 5. Children are unwilling to complete the treatment protocol.

Design outcomes

Primary

Measure	Time frame
Reduction in plaque scores and gingival scoresTimepoint: Baseline, 7 days and 21 days	—

Secondary

Measure	Time frame
Reduction in level of periodontal pathogens.Timepoint: Baseline, 7 days and 21 days	—

Countries

India

Contacts

Public ContactDr Anil V Ankola

KAHERs KLE VISHWANATH KATTI INSTITUTE OF DENTAL SCIENCES

ramsurathkumar1996@gmail.com9095066443

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026