Health Condition 1: J449- Chronic obstructive pulmonary disease, unspecified
Conditions
Interventions
Intervention1: Synbiotic, Protein supplement and exercise: Consumption of Synbiotic and protein supplement dissolved in 150ml of water one serving per day.
Resistance exercise 3 days a week using resi
Sponsors
Rohini Bhadra
Eligibility
Inclusion criteria
Inclusion criteria: COPD with FEV1/FVC <0.7 diagnosed within one year of screening date, both smokers and non-smokers
Exclusion criteria
Exclusion criteria: 1.History of active cardiovascular disease with surgical intervention, malignancy, hepatic or renal insufficiency, malabsorption syndrome 2.History of major surgery, anaemia or tuberculosis in the previous 6 months 3.Acute exacerbation in the last 3 months 4.Consumption of Antibiotic in the last 3 months 5.Consumption of any other nutrition supplement in the previous 15 days 6.Participation in pulmonary rehabilitation programme in the last 3 months at the time of recruitment 7.Specific allergy to any of the components of nutritional supplement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skeletal Muscle Quality Muscle mass (kg), Quadriceps muscle strength (Nm)Timepoint: Baseline and Post intervention(at the end of 12 weeks) | — |
Secondary
| Measure | Time frame |
|---|---|
| Gut microbial profile Serum inflammatory markers (IL-6, TNF a) FRAIL scale Health related quality of lifeTimepoint: Baseline and Post intervention(at the end of 12 weeks) | — |
Countries
India
Contacts
Public ContactRohini Bhadra
St Johns Medical College
Outcome results
None listed