Skip to content

A clinical trial to study the effects of propolis gel in the management of gum disease.

Effect of propolis gel as an adjunct to non-surgical periodontal therapy in the management of chronic periodontitis.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041407
Enrollment
40
Registered
2022-03-28
Start date
Unknown
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Propolis gel: 10% Propolis gel is dispensed subgingivally to the base of the pocket by means of a disposable syringe. It is dispensed once at baseline. Intervention2: Nil: Nil Control I

Sponsors

Dr Lekshmi R
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with chronic periodontitis. 2) Patients willing to take part in the study. 3) Patients in the age group 30 to 65 years without systemic disease. 4) Patients with atleast 20 natural teeth. 5) Patients with periodontal pocket depth of >4mm to 8mm with radiological evidence of bone loss. 6) No history of allergy. 7) Patients willing to take part in the study, and willing to turn up after 21 days and signed on the informed consent.

Exclusion criteria

Exclusion criteria: 1) Pregnant and lactating women. 2) Teeth with endo-perio lesions. 3) Patients used tobacco or tobacco related products. 4) Patients under antibiotic therapy within 3 months of time period from the study. 5) Patients with h/o systemic diseases that can affect the periodontal status 6) Patients who have undergone periodontal surgery. 7) Patients using mouthwash regularly 8) Patients diagnosed with aggressive periodontitis 9) Patients allergic to propolis

Design outcomes

Primary

MeasureTime frame
Checking the effect of propolis gel on the CFU of periodontopathic microorganisms.Timepoint: At the baseline visit and at 21 days

Secondary

MeasureTime frame
Changes in plaque index(PI),gingival bleeding index(GBI), gingival index(GI), pocket probing depth (PPD) and clinical attachment level(CAL)Timepoint: At the baseline visit and at 21 days.

Countries

India

Contacts

Public ContactDr Krishna Kripal

Rajarajeswari dental college and hospital

kripalkrishna@yahoo.com9632597504

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026