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Effect of steroid in prevention of low blood calcium level in patient undergoing thyroid surgery.

Use of Prophylactic Steroid To Prevent Hypocalcemia In Patient Undergoing Thyroidectomy:Randomized controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041396
Enrollment
80
Registered
2022-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexamethasone: Single Dose- 0.1mg/kg body weight(approx 2ml of 8mg dexamethasone) , Intravenous, 60 min before induction of anesthesia. Control Intervention1: 0.9% Normal Saline: 2 ml o

Sponsors

Yashwant Singh Rathore
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.No preoperative voice dysfunction. 2. No preoperative corrected hypocalcemia. 3. Patient requiring total/neartotal thyroidectomy. 4. Normal preoperative serum calcium and iPth.

Exclusion criteria

Exclusion criteria: 1. Refusal to give consent. 2. History of head and neck surgery and previous irradiation. 3. Known vocal cord dysfunction on laryngoscopy. 4. Contraindication to use dexamethasone. stomach and duodenal ulcer disease currently or in the past. 5. taking medications that affect calcium metabolism: anti-resorptive drugs, anabolic drugs,thiazide diuretics, furosemide, proton pump inhibitors, antacids. 6. Staged thyroidectomy will not be included in study.(like completion thyroidectomy) 7. Thyroid malignancy with extrathyroid extension or requiring LN dissection will be excluded from study.

Design outcomes

Primary

MeasureTime frame
To study effectiveness of prophylactic steroid in prevention of hypocalcemia both clinically and laboratory in patient undergoing total/neartotal thyroidectomy.Timepoint: CALCIUM level will be measured before the operation then CALCIUM level after 6hr, 24hr, 48hr and 2weeks after surgery—

Secondary

MeasureTime frame
1 To study the effect of steroid on post-operative voice changes using GRBAS scale 2 To study demographic data of the patient 3 To study other measure like postoperative pain and vomiting in these patientTimepoint: 6hr, 24hr, 48hr and 2weeks after surgery—

Countries

India

Contacts

Public ContactAnurag Kushwaha

All India Institute of Medical Sciences

dryashvant.r@gmail.com9911337726

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026