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Effect of ondansetron (Anti Vomitting drug) injection on Blood pressure, heart rate in delivery by operation cases: A trial in a tertiary care institute in southern Rajasthan

Effect of ondansetron administration on haemodynamic status in caesarean cases: A double blind randomized control trial in a tertiary care institute in southern Rajasthan

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041395
Enrollment
150
Registered
2022-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-01-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O749- Complication of anesthesia duringlabor and delivery, unspecified

Interventions

Intervention1: MAINTENANCE OF HEMODYNAMIC STABILITY AND PREVENTION OF COMPLICATIONS DURING SPINAL ANESTHESIA: Effect of ondansetron administration on haemodynamic status in caesarean cases Control Int

Sponsors

Department of Anesthesiology RNT medical college Udaipur Rajasthan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Pregnant female patients, taken up for cesarean section under spinal anaesthesia for various indications like previous cesarean section, breech, oligo-hydroamnios, cephalopelvic disproportion, pregnancy following infertility treatment, post datism, cord around neck, non-progress of labour

Exclusion criteria

Exclusion criteria: Emergency indication of cesarean section like antepartum hemorrhage, placenta previa, abruptio placentae, fetal distress, obstructed labour, umbilical cord prolapse, hand prolapse, or patient in labor pains,patients having coagulation abnormalities or on anticoagulants, Patients having associated systemic illness (hypo/ hyperthyroidism, diabetic, neuromuscular diseases, ischemic/ valvular/ congenital heart diseases, psychiatric, hematological disorder),contraindications for spinal anesthesia, history of seizures, coma, neurological signs or symptoms (Eclampsia), patient refusal to participate in study,any allergy to local anaesthetic, Obese (weight > 100 Kg), short stature (height

Design outcomes

Secondary

MeasureTime frame
To determine the preventive and therapeutic role of ondansetron on these complications i.e. Intra-operative nausea vomiting, pruritus, shivering .Timepoint: After spinal anesthesia till completion of surgery;To quantify therapeutic vasopressor dose requirement for correction of hypotension.Timepoint: After spinal anesthesia till completion of surgery—

Primary

MeasureTime frame
To measure the effect of ondansetron administration 20 minutes prior to spinal anesthesia on hemodynamic statusTimepoint: Every 5 minutes After spinal anesthesia till completion of Caesarian Section Intraoperative only—

Countries

India

Contacts

Public ContactDr Chandra Prakash Sharma

RNT medical college,Udaipur, Rajasthan

devendra.anaes@yahoo.in

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026