FindTrial
Sign In

Evaluation of various bone forming material for bone preservation after tooth removal.

comparison of clinical and radiographic assessment of efficacy of eggshell-derived nanohydroxyapatite (EnHA) and demineralized freeze dried bone allograft(DFDBA), both covered with platelet-rich fibrin (PRF) in socket preservation - a randomized controlled clinical study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2022/03/041386
Enrollment
20
Registered
2022-03-25
Start date
Unknown
Completion date
Unknown
Last updated
2022-10-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K039- Disease of hard tissues of teeth,unspecified

Interventions

Intervention1: Egg shell derived hydroxyapatite: eggshell-derived nanohydroxyapatite (EnHA) covered with platelet-rich fibrin (PRF) for socket preservation and observed over a period of 4 months Contr

Sponsors

Dr Neha V Nainoor
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients consenting to be a part of the study and have agreed for periodic recall. 2. Systemically healthy patients (ASA-I) between the age group of 18-50 years of either gender requiring bilaterally symmetrical mandibular molar extractions. 3. Patients consenting to standard sterile phlebotomy technique for PRF preparation. 4. Presence of teeth adjacent to the extraction socket.

Exclusion criteria

Exclusion criteria: 1. Patients with a known history of diabetes mellitus, endocrine and bone disorders. 2. Patients with immunosuppressive conditions. 3. Pregnant patients. 4. Patients with poor oral hygiene 5. Patients with acute infections.

Design outcomes

Primary

MeasureTime frame
1. To clinically assess pain, wound healing, in bilaterally symmetrical mandibular molar extraction sockets filled with eggshell-derived nanohydroxyapatite (EnHA) covered with PRF as barrier membrane. 2. To clinically assess pain, wound healing in bilaterally symmetrical mandibular molar extraction sockets filled with DFDBA covered with PRF as a barrier membrane. 3. To radiologically assess bone density, changes in lamina dura and crestal bone level in bilaterally symmetrical mandibular molar extraction sockets filled with eggshell-derived nanohydroxyapatite (EnHA) covered with PRF as barrier membrane. 4. To radiologically assess bone density, changes in lamina dura and crestal bone level in bilaterally symmetrical mandibular molar extraction sockets filled with DFDBA covered with PRF as a barrier membrane. 5. To compare the effect of EnHA covered with PRF and DFDBA covered with PRF in bilaterally symmetrical mandibular molar extraction sockets. Timepoint: 1st month, 4th month—

Secondary

MeasureTime frame
Adequate bone width and height Better periodontal health Timepoint: 1st month, 4th month—

Countries

India

Contacts

Public ContactDr Shobha E S

Dayananda Sagar College Of Dental Sciences

shobha_es@yahoo.com9880821614

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026