This study is to Compare the Postoperative Pain Relief Effect of Intraperitoneal Instillation of Ropivacaine with Fentanyl versus Ropivacaine with Dexmedetomidine in Laparoscopic Gynaecologic Surgeries

Comparision of Intraperitoneal Instillation of Ropivacaine (0.2%) with Fentanyl versus Ropivacaine (0.2%) with Dexmedetomidine For Postoperative Analgesia after Laparoscopic Gynaecologic Surgeries :A Prospective Randomized Double Blind Clinical Study.

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041354

Enrollment

Registered

2022-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intraperitoneal Instillation of Ropivacaine with Fentanyl: At the end of Surgery (duration of surgery 60 to 90 minutes),after peritoneal wash and suctioning ,patient will receive 32 ml

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patient Posted for elective Laparoscopic surgeries in Gynaecology. 2)American society of Anaesthesiologists physical status 1 and 2

Exclusion criteria

Exclusion criteria: 1)Patients who refuse to give consent 2)Patient having allergy to study drugs 3)Patients with history of Cardiovascular diseases (likes IHD and uncontrolled hypertension)and Respiratory diseases ( likes COPD and asthma) 4)Patients taking beta blocking agents 5) Those patients who requre peritoneal drain after surgery 6)chronic pain syndrome of neurologic diseases

Design outcomes

Primary

Measure	Time frame
To compare the analgesic effect by measuring duration of post operative pain relief using visual analogue scale (VAS)scoreTimepoint: To assess post operative pain using visual analogue scale (VAS)score at 30 minutes interval postoperatively upto 2 hours then at 2 hours interval upto 12 hours and then 6 hours interval upto 24 hours.	—

Secondary

Measure	Time frame
1) TO compare the analgesic effect by measuring number of rescue analgesics requred in first 24 hours 2)To monitor pulse rate ,blood pressure,oxygen saturation(SPO2) and end tidal CO2 3)To monitor side effects if any like nausea,vomitting,pruritus,bradycardia,hypotension,sedation and respiratory depressionTimepoint: At 30 minutes interval postoperatively upto 2 hours and then at 2 hourly interval upto 12 hoursand then at 6 hourly interval upto 24 hours.	—

Measure

Time frame

1) TO compare the analgesic effect by measuring number of rescue analgesics requred in first 24 hours 2)To monitor pulse rate ,blood pressure,oxygen saturation(SPO2) and end tidal CO2 3)To monitor side effects if any like nausea,vomitting,pruritus,bradycardia,hypotension,sedation and respiratory depressionTimepoint: At 30 minutes interval postoperatively upto 2 hours and then at 2 hourly interval upto 12 hoursand then at 6 hourly interval upto 24 hours.

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Countries

India

Contacts

Public ContactDr Mamta Patel

Government Medical College,Vadodara

mgpatel111@yahoo.com9825453024

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026