A Clinical Trial to Study The Effect Of Dexmedetomidine and Clonidine as an adjuvant to Bupivacaine 0.25% in supraclavicular brachial plexus block under ultrasound guidance

Comparison of Dexmedetomidine and Clonidine as an adjuvant to Bupivacaine 0.25% in supraclavicular brachial plexus block under ultrasound guidance : A prospective randomised double blind studyÂ Â

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2022/03/041349

Enrollment

Registered

2022-03-24

Start date

Unknown

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical Health Condition 4: V871- Person injured in collision between other motor vehicle and two- or three-wheeled motor vehicle (traffic) Health Condition 5: S529- Unspecified fracture of forearm

Interventions

Intervention1: Dexmedetomidine: Dexmedetomidine 100mcg added to 29ml of 0.25%bupivacaine,single dose Control Intervention1: Clonidine: Clonidine 100mcg added to 29 ml of 0.25% bupivacaine, single dos

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I and II patients of either sex Aged between 18 to 65 years and normal BMI Elective upper limb orthopaedic surgeries

Exclusion criteria

Exclusion criteria: Patients with severe medical comorbidities and local site infection Patients receiving adrenoceptor agonist or antagonist therapy

Design outcomes

Primary

Measure	Time frame
To study duration of analgesia and time to request of rescue analgesia in first 24hours post surgery Timepoint: first 30 minutes post surgery and then every 2nd hourly till patient requests for rescue analgesia	—

Secondary

Measure	Time frame
Time Of Onset And Duration Of Sensory And Motor Blockade and Any other Side Effects Timepoint: first 30 minutes after surgery and every 2nd hourly thereafter	—

Countries

India

Contacts

Public ContactYathish N

SANJAY GANDHI INSTITUTE OF TRAUMA AND ORTHOPAEDICS

YATHISH_HONKAN@YAHOO.COM9964277476

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026